“Ukatamanga weka utamangisa, tikatamanga awili, tifikapatali" - When you run alone, you run fast. When you run together, you run further - Zambian Proverb


Research and Training Programme

Publications 2012

Trends in Childhood Tuberculosis in Zambia: A Situation Analysis. Kapata N, Chanda-Kapata P, O'Grady J, Bates M, Mwaba P, Janssen S, Marais B, Cobelens F, Grobusch M, Zumla A. J Trop Pediatr. 2012 Dec 12. [Epub ahead of print]

HIV Case Notification Rates in the Kingdom of Saudi Arabia over the Past Decade (2000-2009). Mazroa MA, Kabbash IA, Felemban SM, Stephens GM, Al-Hakeem RF, Zumla AI, Memish ZA. PLoS One. 2012;7(9)

Travel medicine. Zumla A, Behrens RH, Memish ZA. Infect Dis Clin North Am. 2012 Sep;26(3)

Eosinophilia in the returning traveler. Ustianowski A, Zumla A. Infect Dis Clin North Am. 2012 Sep;26(3):781-9

New global estimates of malaria deaths. Bates M, O'Grady J, Mudenda V, Shibemba A, Zumla A. Lancet. 2012 Aug 11;380(9841):560-1

Evaluation of the burden of unsuspected pulmonary tuberculosis and co-morbidity with non-communicable diseases in sputum producing adult inpatients. Bates M, O'Grady J, Mwaba P, Chilukutu L, Mzyece J, Cheelo B, Chilufya M, Mukonda L, Mumba M, Tembo J, Chomba M, Kapata N, Rachow A, Clowes P, Maeurer M, Hoelscher M, Zumla A. PLoS One. 2012;7(7):e40774. Epub 2012 Jul 27. PDF

Leprosy trends in Zambia 1991-2009. Kapata N, Chanda-Kapata P, Grobusch MP, O'Grady J, Bates M, Mwaba P, Zumla A. Trop Med Int Health. 2012 Jul 29

Evaluation of the Xpert MTB/RIF Assay at a Tertiary Care Referral Hospital in a Setting Where Tuberculosis and HIV Infection Are Highly Endemic. O'Grady J, Bates M, Chilukutu L, Mzyece J, Cheelo B, Chilufya M, Mukonda L, Mumba M, Tembo J, Chomba M, Kapata N, Maeurer M, Rachow A, Clowes P, Hoelscher M, Mwaba P, Zumla A. Clin Infect Dis. 2012 Nov;55(9):1171-8 PDF

Mass gatherings medicine and global health security. Al Rabeeah A, Memish ZA, Zumla A, Shafi S, McCloskey B, Moolla A, Barbeschi M, Heymann D, Horton R. Lancet. 2012 Jul 7;380(9836):3-4

Tuberculosis trends in Saudis and non-Saudis in the Kingdom of Saudi Arabia--a 10 year retrospective study (2000-2009). Abouzeid MS, Zumla AI, Felemban S, Alotaibi B, O'Grady J, Memish ZA. PLoS One. 2012;7(6):e39478. Epub 2012 Jun 20

Diagnosis of extrapulmonary tuberculosis using the Xpert(®) MTB/RIF assay. Lawn SD, Zumla AI. Expert Rev Anti Infect Ther. 2012 Jun;10(6):631-5

The Global Fund Round 11 cancellation fiasco: turning disaster into opportunity? Zumla A. Int J Tuberc Lung Dis. 2012;16(3):285-6

Preface: tropical diseases. Zumla A, Keiser J. Infect Dis Clin North Am. 2012 Jun;26(2):xv-xvii. Epub 2012 Apr 4

Tropical diseases: definition, geographic distribution, transmission, and classification. Zumla A, Ustianowski A. Infect Dis Clin North Am. 2012 Jun;26(2):195-205. Epub 2012 Apr 2

Intravenous Immunoglobulin (IVIg) for Refractory and Difficult-to-treat Infections. Ferrara G, Zumla A, Maeurer M. Am J Med. 2012 Oct;125(10

Scaling up interventions to achieve global tuberculosis control: progress and new developments. Raviglione M, Marais B, Floyd K, Lönnroth K, Getahun H, Migliori GB, Harries AD, Nunn P, Lienhardt C, Graham S, Chakaya J, Weyer K, Cole S, Kaufmann SH, Zumla A. Lancet. 2012 May 19;379(9829):1902-13. Review. Erratum in: Lancet. 2012 Jun 16;379(9833):2242.

SeekTB, a two-stage multiplex real-time-PCR-based method for differentiation of the Mycobacterium tuberculosis complex. Reddington K, Zumla A, Bates M, van Soolingen D, Niemann S, Barry T, O'Grady J. J Clin Microbiol. 2012 Jul;50(7):2203-6. doi: 10.1128/JCM.00718-12. Epub 2012 May 2.

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities. McNerney R, Maeurer M, Abubakar I, Marais B, McHugh TD, Ford N, Weyer K, Lawn S, Grobusch MP, Memish Z, Squire SB, Pantaleo G, Chakaya J, Casenghi M, Migliori GB, Mwaba P, Zijenah L, Hoelscher M, Cox H, Swaminathan S, Kim PS, Schito M, Harari A, Bates M, Schwank S, O'Grady J, Pletschette M, Ditui L, Atun R, Zumla A. J Infect Dis. 2012 May 15;205 Suppl 2:S147-58

Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB and XDR-TB: systematic review and meta-analysis. Sotgiu G, Centis R, D'Ambrosio L, Alffenaar J, Anger H, Caminero J, Castiglia P, De Lorenzo S, Ferrara G, Koh W, Schecter G, Shim T, Singla R, Skrahina A, Spanevello A, Udwadia Z, Villar M, Zampogna E, Zellweger J, Zumla A, Migliori GB. Eur Respir J. 2012 Apr 10.

Interaction between HIV and Mycobacterium tuberculosis: HIV-1-induced CD4 T-cell depletion and the development of active tuberculosis. Geldmacher C, Zumla A, Hoelscher M. Curr Opin HIV AIDS. 2012 May;7(3):268-75.

Scale-up of TB and HIV programme collaborative activities in Zambia - a 10-year review. Kapata N, Chanda-Kapata P, Grobusch MP, O'Grady J, Schwank S, Bates M, Jansenn S, Mwinga A, Cobelens F, Mwaba P, Zumla A.Trop Med Int Health. 2012 Jun;17(6):760-6

Drug-resistant tuberculosis--current dilemmas, unanswered questions, challenges, and priority needs. Zumla A, Abubakar I, Raviglione M, Hoelscher M, Ditiu L, McHugh TD, Squire SB, Cox H, Ford N, McNerney R, Marais B, Grobusch M, Lawn SD, Migliori GB, Mwaba P, O'Grady J, Pletschette M, Ramsay A, Chakaya J, Schito M, Swaminathan S, Memish Z, Maeurer M, Atun R. J Infect Dis. 2012 May 15;205 Suppl 2:S228-40.

European union standards for tuberculosis care. Migliori GB, Zellweger JP, Abubakar I, Ibraim E, Caminero JA, De Vries G, D'Ambrosio L, Centis R, Sotgiu G, Menegale O, Kliiman K, Aksamit T, Cirillo DM, Danilovits M, Dara M, Dheda K, Dinh-Xuan AT, Kluge H, Lange C, Leimane V, Loddenkemper R, Nicod LP, Raviglione MC, Spanevello A, Thomsen VØ, Villar M, Wanlin M, Wedzicha JA, Zumla A, Blasi F, Huitric E, Sandgren A, Manissero D. Eur Respir J. 2012 Apr;39(4):807-19.

Rational use of anti-tuberculosis drugs in the EU: better patient care and less drug resistance. Zumla A, Blasi F, Raviglione M. Eur Respir J. 2012 Apr;39(4):802-4.

Adjunct immunotherapies for tuberculosis. Uhlin M, Andersson J, Zumla A, Maeurer M. J Infect Dis. 2012 May 15;205 Suppl 2:S325-34. Epub 2012 Mar 29.

Investing in improved performance of national tuberculosis programs reduces the tuberculosis burden: analysis of 22 high-burden countries, 2002-2009. Akachi Y, Zumla A, Atun R. J Infect Dis. 2012 May 15;205 Suppl 2:S284-92

Innovative trial designs are practical solutions for improving the treatment of tuberculosis. Phillips PP, Gillespie SH, Boeree M, Heinrich N, Aarnoutse R, McHugh T, Pletschette M, Lienhardt C, Hafner R, Mgone C, Zumla A, Nunn AJ, Hoelscher M. J Infect Dis. 2012 May 15;205 Suppl 2:S250-7

Global fund financing of tuberculosis services delivery in prisons. Lee D, Lal SS, Komatsu R, Zumla A, Atun R. J Infect Dis. 2012 May 15;205 Suppl 2:S274-83.

Controversies and unresolved issues in tuberculosis prevention and control: a low-burden-country perspective. Abubakar I, Stagg HR, Cohen T, Mangtani P, Rodrigues LC, Pimpin L, Watson JM, Squire SB, Zumla A. J Infect Dis. 2012 May 15;205 Suppl 2:S293-300.

Tuberculosis and tuberculosis/HIV/AIDS-associated mortality in Africa: the urgent need to expand and invest in routine and research autopsies. Mudenda V, Lucas S, Shibemba A, O'Grady J, Bates M, Kapata N, Schwank S, Mwaba P, Atun R, Hoelscher M, Maeurer M, Zumla A. J Infect Dis. 2012 May 15;205 Suppl 2:S340-6.

New drugs for the treatment of tuberculosis: needs, challenges, promise, and prospects for the future. Lienhardt C, Raviglione M, Spigelman M, Hafner R, Jaramillo E, Hoelscher M, Zumla A, Gheuens J. J Infect Dis. 2012 May 15;205 Suppl 2:S241-9.

The immunological footprint of Mycobacterium tuberculosis T-cell epitope recognition. Axelsson-Robertson R, Magalhaes I, Parida SK, Zumla A, Maeurer M. J Infect Dis. 2012 May 15;205 Suppl 2:S301-15.

Eliminating tuberculosis and tuberculosis-HIV co-disease in the 21st century: key perspectives, controversies, unresolved issues, and needs. Zumla A, Atun R, Maeurer M, Kim PS, Jean-Philippe P, Hafner R, Schito M. J Infect Dis. 2012 May 15;205 Suppl 2:S141-6.

Rational development of adjunct immune-based therapies for drug-resistant tuberculosis: hypotheses and experimental designs. Zumla A, Maeurer M.J Infect Dis. 2012 May 15;205 Suppl 2:S335-9.

A sustainable agenda for tuberculosis control and research. Raviglione M, Zumla A, Marais B, Horton R, Motsoaledi A.Lancet. 2012 Mar 24;379(9821):1077-8.

Role of fluorine 18 fluorodeoxyglucose positron emission tomography-computed tomography in focal and generalized infectious and inflammatory disorders. Haroon A, Zumla A, Bomanji J. Clin Infect Dis. 2012 May;54(9):1333-41.

Surgery and tuberculosis.Cummings I, O'Grady J, Pai V, Kolvekar S, Zumla A.Curr Opin Pulm Med. 2012 May;18(3):241-5.

Operational research and MDG tuberculosis control targets. Zumla A, Cobelens F. Lancet Infect Dis. 2012 Apr;12(4):262-3.

Risk factors associated with pulmonary tuberculosis: smoking, diabetes and anti-TNFα drugs. Ferrara G, Murray M, Winthrop K, Centis R, Sotgiu G, Migliori GB, Maeurer M, Zumla A. Curr Opin Pulm Med. 2012 May;18(3):233-40.

Advancing the development of tuberculosis therapy. Zumla A, Hafner R, Lienhardt C, Hoelscher M, Nunn A. Nat Rev Drug Discov. 2012 Mar 1;11(3):171-2.

Analogies and metaphors in clinical medicine.Masukume G, Zumla A. Clin Med. 2012 Feb;12(1):55-6.

Killer respiratory tract infections: time to turn the tide. Zumla A.Curr Opin Pulm Med. 2012 May;18(3):173-4.

Pattern recognition and cellular immune responses to novel Mycobacterium tuberculosis-antigens in individuals from Belarus. Ahmed RK, Rohava Z, Balaji KN, Hoffner SE, Gaines H, Magalhaes I, Zumla A, Skrahina A, Maeurer MJ. BMC Infect Dis. 2012 Feb 15;12:41.

Thoracic empyema: a 12-year study from a UK tertiary cardiothoracic referral centre.Marks DJ, Fisk MD, Koo CY, Pavlou M, Peck L, Lee SF, Lawrence D, Macrae MB, Wilson AP, Brown JS, Miller RF, Zumla AI. PLoS One. 2012;7(1):e30074. Epub 2012 Jan 20.

Tuberculosis in prisons: anatomy of global neglect. O'Grady J, Maeurer M, Atun R, Abubakar I, Mwaba P, Bates M, Kapata N, Ferrara G, Hoelscher M, Zumla A. Eur Respir J. 2011 Oct;38(4):752-4.

Tackling the spread of drug-resistant tuberculosis in Europe. Abubakar I, Dara M, Manissero D, Zumla A. Lancet. 2012 Jan 28;379(9813)