“Ukatamanga weka utamangisa, tikatamanga awili, tifikapatali" - When you run alone, you run fast. When you run together, you run further - Zambian Proverb


Research and Training Programme

Publications 2010

Is the eradication of tuberculosis 'yesterday's ambition' or 'tomorrow's triumph'? Zumla A, Grange JM. Clin Med. 2010 Oct;10(5):450-3.

Tuberculosis control is crucial to achieve the MDGs. Atun R, Raviglione M, Marais B, Zumla A. Lancet. 2010 Sep 18;376(9745):940-1.

Extensively drug-resistant tuberculosis (XDR-TB) among health care workers in South Africa. Jarand J, Shean K, O'Donnell M, Loveday M, Kvasnovsky C, Van der Walt M, Adams S, Willcox P, O'Grady J, Zumla A, Dheda K. Trop Med Int Health. 2010 Oct;15(10):1179-84.

Pneumocystis jirovecii in pleural infection: a nucleic acid amplification study. Wrightson JM, Rahman NM, Novak T, Huggett JF, Maskell NA, Zumla A, Miller RF, Davies RJ. Thorax. 2011 May;66(5):450-1.

Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis. Caminero JA, Sotgiu G, Zumla A, Migliori GB. Lancet Infect Dis. 2010 Sep;10(9):621-9.

Extensively drug-resistant tuberculosis: epidemiology and management challenges. Dheda K, Warren RM, Zumla A, Grobusch MP. Infect Dis Clin North Am. 2010 Sep;24(3):705-25.

Emerging respiratory infections in the 21st century. Preface. Zumla A, Yew WW, Hui DS. Infect Dis Clin North Am. 2010 Sep;24(3):xiii-xvi.

Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa. Migliori GB, Dheda K, Centis R, Mwaba P, Bates M, O'Grady J, Hoelscher M, Zumla A. Trop Med Int Health. 2010 Sep;15(9):1052-66.

Research capacity strengthening in African countries. Mwaba P, Bates M, Green C, Kapata N, Zumla A. Lancet. 2010 May 29;375(9729):1874.

Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study. Dheda K, Shean K, Zumla A, Badri M, Streicher EM, Page-Shipp L, Willcox P, John MA, Reubenson G, Govindasamy D, Wong M, Padanilam X, Dziwiecki A, van Helden PD, Siwendu S, Jarand J, Menezes CN, Burns A, Victor T, Warren R, Grobusch MP, van der Walt M, Kvasnovsky C. Lancet. 2010 May 22;375(9728):1798-807.

Scale-up of services and research priorities for diagnosis, management, and control of tuberculosis: a call to action. Marais BJ, Raviglione MC, Donald PR, Harries AD, Kritski AL, Graham SM, El-Sadr WM, Harrington M, Churchyard G, Mwaba P, Sanne I, Kaufmann SH, Whitty CJ, Atun R, Zumla A. Lancet. 2010 Jun 19;375(9732):2179-91.

Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice. Wallis RS, Pai M, Menzies D, Doherty TM, Walzl G, Perkins MD, Zumla A. Lancet. 2010 May 29;375(9729):1920-37.

Variation in gamma interferon responses to different infecting strains of Mycobacterium tuberculosis in acid-fast bacillus smear-positive patients and household contacts in Antananarivo, Madagascar. Rakotosamimanana N, Raharimanga V, Andriamandimby SF, Soares JL, Doherty TM, Ratsitorahina M, Ramarokoto H, Zumla A, Huggett J, Rook G, Richard V, Gicquel B, Rasolofo-Razanamparany V; VACSEL/VACSIS Study Group. Clin Vaccine Immunol. 2010 Jul;17(7):1094-103.

World TB Day 2010: eradicating tuberculosis in sub-Saharan Africa needs effective and committed north-south partnerships. Marais B, Hoelscher M, Mwaba P, Dheda K, Zumla A.S Afr Med J. 2010 Mar 8;100(3):153-4.

Feasibility and diagnostic utility of antigen-specific interferon-gamma responses for rapid immunodiagnosis of tuberculosis using induced sputum. Cashmore TJ, Peter JG, van Zyl-Smit RN, Semple PL, Maredza A, Meldau R, Zumla A, Nurse B, Dheda K. PLoS One. 2010 Apr 28;5(4):e10389. doi: 10.1371/journal.pone.0010389.

Cerebrospinal T-cell responses aid in the diagnosis of tuberculous meningitis in a human immunodeficiency virus- and tuberculosis-endemic population. Patel VB, Singh R, Connolly C, Coovadia Y, Peer AK, Parag P, Kasprowicz V, Zumla A, Ndung'u T, Dheda K. Am J Respir Crit Care Med. 2010 Aug 15;182(4):569-77.

Drug-resistant tuberculosis in the European Union: opportunities and challenges for control. Fears R, Kaufmann S, Ter Meulen V, Zumla A; EASAC Working Group. Tuberculosis (Edinb). 2010 May;90(3):182-7.

Urine for the diagnosis of tuberculosis: current approaches, clinical applicability, and new developments. Peter J, Green C, Hoelscher M, Mwaba P, Zumla A, Dheda K. Curr Opin Pulm Med. 2010 May;16(3):262-70.

Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples. Dheda K, Davids V, Lenders L, Roberts T, Meldau R, Ling D, Brunet L, van Zyl Smit R, Peter J, Green C, Badri M, Sechi L, Sharma S, Hoelscher M, Dawson R, Whitelaw A, Blackburn J, Pai M, Zumla A. PLoS One. 2010 Mar 24;5(3):e9848.

Thoracic empyema: current opinions in medical and surgical management. Lee SF, Lawrence D, Booth H, Morris-Jones S, Macrae B, Zumla A. Curr Opin Pulm Med. 2010 May;16(3):194-200.

Trials and tribulations of an African-led research and capacity development programme: the case for EDCTP investments. Zumla A, Huggett J, Dheda K, Green C, Kapata N, Mwaba P. Trop Med Int Health. 2010 Apr;15(4):489-94.

Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis. Pooran A, Booth H, Miller RF, Scott G, Badri M, Huggett JF, Rook G, Zumla A, Dheda K. BMC Pulm Med. 2010 Feb 22;10:7.

The relentless and persistent global threat of a range of pulmonary infections. Zumla A. Curr Opin Pulm Med. 2010 May;16(3):169-70.

Comparison of same day versus delayed enumeration of TB-specific T cell responses. Lenders LM, Meldau R, van Zyl-Smit RN, Woodburne V, Maredza A, Cashmore TJ, Semple PL, Badri M, Zumla A, Dheda K. J Infect. 2010 May;60(5):344-50. doi: 10.1016/j.jinf.2010.01.012. Epub 2010 Feb 10.

Community-based interventions to reduce maternal mortality. Ahmed Y, Mwaba P, Grange J, Green C, Zumla A. Lancet. 2010 Feb 6;375(9713):457-8; author reply 458-9.

Biomarkers for tuberculosis disease activity, cure, and relapse. Wallis RS, Wang C, Doherty TM, Onyebujoh P, Vahedi M, Laang H, Olesen O, Parida S, Zumla A. Lancet Infect Dis. 2010 Feb;10(2):68-9.

Tuberculosis in association with HIV/AIDS emerges as a major nonobstetric cause of maternal mortality in Sub-Saharan Africa. Grange J, Adhikari M, Ahmed Y, Mwaba P, Dheda K, Hoelscher M, Zumla A. Int J Gynaecol Obstet. 2010 Mar;108(3):181-3.

World TB Day 2010--new innovations are required for enhancing the global fight against tuberculosis: the 'captain of all these men of death'. Grange J, Mwaba P, Dheda K, Höelscher M, Zumla A. Trop Med Int Health. 2010 Mar;15(3):274-6.

Global lung health: the colliding epidemics of tuberculosis, tobacco smoking, HIV and COPD. van Zyl Smit RN, Pai M, Yew WW, Leung CC, Zumla A, Bateman ED, Dheda K. nEur Respir J. 2010 Jan;35(1):27-33.

Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study. Tissari P, Zumla A, Tarkka E, Mero S, Savolainen L, Vaara M, Aittakorpi A, Laakso S, Lindfors M, Piiparinen H, Mäki M, Carder C, Huggett J, Gant V. nLancet. 2010 Jan 16;375(9710):224-30.