The University of Zambia - University College London Medical School (UNZA-UCLMS) Research & Training Programme was founded in 1994 as an African-led south-north medical research and development organization based at the University of Zambia School of Medicine and Zambia's national referral centre, the University Teaching Hospital. Through a rich history of high impact outputs UNZA-UCLMS has grown into a world-leading medical research organization, obtaining substantial competitive grant funding for training medical and laboratory personnel, building clinical trial capacity and laboratory infrastructure, and publishing research in high impact factor journals which has changed World Health Organization policy for TB and TB/HIV.
Please click on the logos to see details of individual projects
Zumla et al... 2015: Nat Rev Drug Discov. Towards host-directed therapies for tuberculosis.
Bates et al... 2015. Lancet Infect Dis. Burden of tuberculosis at post mortem in inpatients at a tertiary referral centre in sub-Saharan Africa: a prospective descriptive autopsy study.
Tembo et al... 2015. Clin. Infect. Dis. Prevalence and Risk Factors for Betaherpesvirus DNAemia in Children >3 Weeks and <2 Years of Age Admitted to a Large Referral Hospital in Sub-Saharan Africa.
Mfinanga et al... 2014: Lancet Infect Dis. Early versus delayed initiation of highly active antiretroviral therapy for HIV-positive adults with newly diagnosed pulmonary tuberculosis (TB-HAART): a prospective, international, randomised, placebo-controlled trial.
Mwaanza et al... 2013: Clin infect Dis. High rates of congenital cytomegalovirus infection linked with maternal HIV infection among neonatal admissions at a large referral centre in sub-Saharan Africa
Cotton et al... 2013: Lancet. Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study.
Memish et al... 2013: N Eng J Med. Middle East Respiratory Syndrome Coronavirus infections in health care workers
Assiri et al... 2013 Lancet Infect Dis. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study.
Zumla et al… 2013: N Engl J Med. Tuberculosis
Bates et al... 2013: Lancet Infect Dis. Evaluation of the Xpert® MTB/RIF assay for diagnosis of tuberculosis in sub-Saharan African children using gastric lavage aspirates: a prospective descriptive study
Raviglione et al... 2012: The Lancet. Scaling up interventions to achieve global tuberculosis control: progress and new developments.
O'Grady et al... 2012: Clinical Infect Dis. Evaluation of the Xpert(R) MTB/RIF assay at a tertiary referral hospital in a high TB/HIV endemic setting.
Tissari et al... 2010: The Lancet. Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study.
Dheda et al... 2010: The Lancet. Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa.
Nunn et al... 2008: British Medical Journal. Role of co-trimoxazole prophylaxis in reducing mortality in HIV infected adults being treated for tuberculosis: randomised clinical trial.
Chintu et al... 2004: The Lancet. Co-trimoxazole as prophylaxis against opportunistic infections in HIV- infected Zambian children. A double blind randomized placebo-controlled trial.
Mwaba et al... 2003: The Lancet. Use of dried whole blood spots to measure CD4+ lymphocyte counts in HIV-1-infected
Mwaba et al... 2003: The Lancet. Whole blood versus plasma spots for measurement of HIV-1 viral load in HIV-infected African patients.
Mwinga et al... 2002: The Lancet. Mycobacterium vaccae (SRL172) immunotherapy as an adjunct to standard antituberculosis treatment in HIV-infected adults with pulmonary tuberculosis: a randomised placebo-controlled trial.
Chintu et al... 2002: The Lancet. Lung diseases at necropsy in African children dying from respiratory illnesses: a descriptive necropsy study.
Durban Immunotherapy Trial Group 1999: The Lancet. Immunotherapy with Mycobacterium vaccae in patients with newly diagnosed pulmonary tuberculosis: a randomised placebo-controlled trial.
Luo et al... 1994: Tubercle & Lung Disease. Tuberculosis and the Human immunodeficiency Virus infection in Zambian children: changing seroprevalence and evaluation of a thiacetazone-free regimen.
Chintu et al... 1993: Archives of Disease in Childhood. Cutaneous hypersensitivity reactions due to thiacetazone in Zambian children infected with tuberculosis and the human immunodeficiency virus.